Welcome

to

the

future

of

neurotherapeutics.

OUR MISSION

At Sculpta Bio, we are dedicated to developing effective treatments for neurodegeneration, mental health, and the aging brain, enabling longer, healthier lives for all. Around the world, millions are losing memories, identities, and futures to diseases we still cannot stop. It is a crisis growing faster than science has kept pace.

But, the past does not have to define our future.

Sculpta is forging a bold new path in neurotherapeutic drug development, powered by cutting edge technology, scientific excellence, and a relentless spirit of urgency. Humanity cannot wait any longer.

Discover how we are challenging the status quo by reshaping the future of brain health.

A BOLD, NEW APPROACH

Protein sculpting therapeutics

Other companies try to drug proteins in the brain to treat disease.
We change them.

Sculpta is the pioneer in protein sculpting therapeutics, drugs that change the structure and function of disease-causing proteins in the brain using programmable RNA medicines. We move beyond “up/down” genomic medicines, offering safer, more specific, and more effective therapies for devastating brain disorders, brought to patients faster.

ADVANCED NEURAL TISSUE ANALYSIS

Quality over quantity

Single cell genomics has revolutionized biological discovery, yet quality is often sacrificed for quantity. The most widely used platforms capture only the very ends of transcripts. AI models trained on this inaccurate data are destined to fail.

Sculpta’s platform captures full-length transcripts, powering our ATLAS AI-platform that is driving unique insights into the neurobiology of human disease.

ACCURATE PRE-CLINICAL MODELS

Human models for human disease

Traditional animal models often fail to capture human-specific disease mechanisms. Our best-in-class human brain organoids platform enables us to discover the root causes of disease and test therapeutics in living human neurons.

Neal Amin, MD, PhD

Founder | CEO

Joshua Berlind

Scientist

Amina Khan, PhD

Research Associate

Bryan van Nimwegen, PhD

Computational Biologist

Mislav Acman

Senior Computational Biologist

Backed by

April 2025

New Publication in Nature

Neal Amin, CEO
Groundbreaking work on modeling human neurosensation for drug development with contributions from Sculpta CEO and Founder Neal Amin.
March 2025

Sculpta Closes $2.6M Funding Round

Sculpta has successfully secured $2.6M in pre-seed funding from six venture capital groups and six angels to accelerate the the development of protein sculpting therapies for devastating brain disorders.

March 2025

New Publication in Neuron

Joshua Berlind, Scientist
Research led by Sculpta scientist Joshua Berlind discovers excitotoxicity pathway in tau-opathies using advanced human brain organoid technology.
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